Learning Objectives 1. See our Privacy Policy and User Agreement for details. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Fluoride toxicity 1. Looks like you’ve clipped this slide to already. See our Privacy Policy and User Agreement for details. Fluoride --A Brief Glimpse into History-- • Fluoride’s ability to inhibit or even reverse the initiation and … YEAR BDS Complaints concerning the gastro-intestinal system in endemic areas are now established as early warning signs of fluoride toxicity. 4. Scribd is the world's largest social reading and publishing site. See our User Agreement and Privacy Policy. About 60 million people in India suffered fluoride poisoning when they drank contaminated groundwater. Some plants that are more susceptible to fluoride toxicity are monocots, including spider plant, lilies, spikes and dracaena. Mechanism after fluoride intake : Once fluoride enters the body either through the blood vessels in the mouth or through the gastrointestinal route, it reaches the various organs and tissues in the body. Twenty four healthy, male albino Wistar rats were Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. No public clipboards found for this slide, Assistant Professor in Public Health Dentistry. no initial burst of fluoride, fluoride is released continually over time.57 Dental material for fillings: composites58 Not all, but some of these materials, used for dental fillings, can contain different types of fluoride such as inorganic salts, leachable glasses, or organic fluoride.59 The fluoride … Knowledge of all aspects of fluoride metabolism is essential for comprehending the biological effects of this ion in humans as well as to drive the prevention (and treatment) of fluoride toxicity. – Continued ingestion of high doses of naturally occurring fluoride will be reflected in changes in the teeth. Groundwater has much more. Fluorosis is a metabolic hard tissue disease caused by ingestion of excessive amount of fluoride, mainly through drinking water. To Explain the pathology of dental and skeletal fluorosis. Although many poisoning incidents go undiagnosed, the number of reports to Poison Control Centers in the U.S. has skyrocketed since the FDA issued its poison warning. FLUORIDE TOXICITY 2. Experimental Design. Fluoride Toxicity: Overview and Examples By David Kennedy, DDS, Amanda Just, MS, Jack Kall, DMD, and Griffin Cole, DDS September 2017 Overview Fluoride Exposure, Toxicity, and Health Effects The sources of human exposure to fluoride have drastically increased since community water fluoridation began in the U.S. in the 1940’s. The solubility of fluoride correlates generally with the degree of toxicity. HOSPITALAND RESEARCH CENTER Lecture on toxic effects of fluoride and pathology of dental and skeletal fluorosis. Fluoride Toxicity. Long-term exposure to fluoride through elevated levels in drinking water leads to skeletal and dental fluorosis. Fluoride ions convert to HF at pH 1.0–2.0 in the gut and are rapidly absorbed. 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